Ikehata, Hironobu: search on Z-Library

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1

Characteristics of mutations generated through digestion with restriction enzyme and ligation in plasmid DNA

Shingo Nakamura, Hironobu Ikehata, Tetsuya Ono

Journal:

Environmental and Molecular Mutagenesis

Year:

2001

Language:

english

File:

PDF, 108 KB

english, 2001

2

Quantitative analysis of UV photolesions suggests that cyclobutane pyrimidine dimers produced in mouse skin by UVB are more mutagenic than those produced by UVC

Ikehata, Hironobu, Mori, Toshio, Douki, Thierry, Cadet, Jean, Yamamoto, Masayuki

Journal:

Photochemical & Photobiological Sciences

Year:

2018

Language:

english

File:

PDF, 2.44 MB

english, 2018

3

Roles of the KEAP1-NRF2 system in mammalian skin exposed to UV radiation

Ikehata, Hironobu, Yamamoto, Masayuki

Journal:

Toxicology and Applied Pharmacology

Year:

2018

Language:

english

File:

PDF, 775 KB

english, 2018

4

The Mechanisms of UV Mutagenesis

IKEHATA, Hironobu, ONO, Tetsuya

Journal:

Journal of Radiation Research

Year:

2011

Language:

english

File:

PDF, 462 KB

english, 2011

5

Mutation theory of aging, assessed in transgenic mice and knockout mice

Tetsuya Ono, Yoshihiko Uehara, Yusuke Saito, Hironobu Ikehata

Journal:

Mechanisms of Ageing and Development

Year:

2002

Language:

english

File:

PDF, 246 KB

english, 2002

6

Effects of calorie restriction on the age-dependent accumulation of mutations in the small intestine of lacZ-transgenic mice

Dongwei He, Yoshihiko Uehara, Maiko Furuya, Hironobu Ikehata, Jun-ichiro Komura, Kazumi Yamauchi, Shizuko Kakinuma, Yi Shang, Yoshiya Shimada, Akira Ootsuyama, Toshiyuki Norimura, Tetsuya Ono

Journal:

Mechanisms of Ageing and Development

Year:

2011

Language:

english

File:

PDF, 307 KB

english, 2011

7

Antigenotoxic effects of p53 on spontaneous and ultraviolet light B–induced deletions in the epidermis of gpt delta transgenic mice

Kenichi Masumura, Yasuteru Sakamoto, Megumi Ikeda, Yasuo Asami, Tetsuya Tsukamoto, Hironobu Ikehata, Yuichi Kuroiwa, Takashi Umemura, Akiyoshi Nishikawa, Masae Tatematsu, Tetsuya Ono, Takehiko Nohmi

Journal:

Environmental and Molecular Mutagenesis

Year:

2011

Language:

english

File:

PDF, 545 KB

english, 2011

8

Absence of Ku70 Gene Obliterates X-Ray-Induced lacZ Mutagenesis of Small Deletions in Mouse Tissues

Yoshihiko Uehara, Hironobu Ikehata, Jun-ichro Komura, Ari Ito, Masaki Ogata, Tsunetoshi Itoh, Ryoichi Hirayama, Yoshiya Furusawa, Koichi Ando, Tatjana Paunesku, Gayle E. Woloschak, Kenshi Komatsu, Shi

Journal:

Radiation Research

Year:

2008

Language:

english

File:

PDF, 1.92 MB

english, 2008

9

Spectrum of spontaneous mutations in a cDNA of the humanhprtgene integrated in chromosomal DNA

Hironobu Ikehata, Toshiaki Akagi, Hiroshi Kimura, Susumu Akasaka, Takesi Kato

Journal:

Molecular Genetics and Genomics

Year:

1989

Language:

english

File:

PDF, 964 KB

english, 1989

10

Shuttle vector system for the analysis of mutational events in mammalian chromosomal DNA

Hironobu Ikehata, Hiroshi Kimura, Takesi Kato

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1989

Language:

english

File:

PDF, 1.02 MB

english, 1989

11

X-Ray- and Ultraviolet-Radiation-Induced Mutations in Muta™ Mouse

Tetsuya Ono, Hironobu Ikehata, Yoshio Hosoi, Bok-Shil Shung, Akihiro Kurishita, Xue Wang, Kazuo Yamamoto, Takayoshi Suzuki and Toshio Sofuni

Journal:

Radiation Research

Year:

1997

Language:

english

File:

PDF, 1.01 MB

english, 1997

12

Comparison of DNA Polymerases .ALPHA., .DELTA., and .EPSILON. of Mouse Cell Line FM3A and Its Temperature-Sensitive Mutant tsFT20.

IKEHATA, HIRONOBU

Journal:

The Tohoku Journal of Experimental Medicine

Year:

1994

Language:

english

File:

PDF, 2.84 MB

english, 1994

13

Significance of CpG Methylation for Solar UV-Induced Mutagenesis and Carcinogenesis in Skin

Hironobu Ikehata, Tetsuya Ono

Journal:

Photochemistry and Photobiology

Year:

2007

Language:

english

File:

PDF, 612 KB

english, 2007

14

Thermolysin improves mutation analysis in skin epidermis from ultraviolet light–irradiated Muta™ Mouse

Hironobu Ikehata, Setsuya Aiba, Hiroaki Ozawa, Tetsuya Ono

Journal:

Environmental and Molecular Mutagenesis

Year:

2001

Language:

english

File:

PDF, 40 KB

english, 2001

15

Mutation spectrum in UVB-exposed skin epidermis of a mildly-affected Xpg-deficient mouse

Feng Wang, Yusuke Saito, Tadahiro Shiomi, Shogo Yamada, Tetsuya Ono, Hironobu Ikehata

Journal:

Environmental and Molecular Mutagenesis

Year:

2006

Language:

english

File:

PDF, 151 KB

english, 2006

16

Role of the Msh2 gene in genome maintenance and development in mouse fetuses

Dongwei He, Yali Chen, Huiying Li, Maiko Furuya, Hironobu Ikehata, Yoshihiko Uehara, Jun-ichiro Komura, Tak W. Mak, Tetsuya Ono

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2012

Language:

english

File:

PDF, 396 KB

english, 2012

17

Absence of Ku70 Gene Obliterates X-Ray-Induced lacZ Mutagenesis of Small Deletions in Mouse Tissues

Uehara, Yoshihiko, Ikehata, Hironobu, Komura, Jun-ichro, Ito, Ari, Ogata, Masaki, Itoh, Tsunetoshi, Hirayama, Ryoichi, Furusawa, Yoshiya, Ando, Koichi, Paunesku, Tatjana, Woloschak, Gayle E., Komatsu,

Journal:

Radiation Research

Year:

2008

Language:

english

File:

PDF, 415 KB

english, 2008

18

Frequent recovery of triplet mutations in UVB-exposed skin epidermis of Xpc-knockout mice

Hironobu Ikehata, Yusuke Saito, Fumitaka Yanase, Toshio Mori, Osamu Nikaido, Tetsuya Ono

Journal:

Year:

2007

Language:

english

File:

PDF, 424 KB

english, 2007

19

Mapping Psoralen Cross-Links at the Nucleotide Level in Mammalian Cells: Suppression of Cross-Linking at Transcription Factor- or Nucleosome-Binding Sites †

Komura, Jun-ichiro, Ikehata, Hironobu, Hosoi, Yoshio, Riggs, Arthur D., Ono, Tetsuya

Journal:

Year:

2001

Language:

english

File:

PDF, 297 KB

english, 2001

20

Action Spectrum Analysis of UVR Genotoxicity for Skin: The Border Wavelengths between UVA and UVB Can Bring Serious Mutation Loads to Skin

Ikehata, Hironobu, Higashi, Shoichi, Nakamura, Shingo, Daigaku, Yasukazu, Furusawa, Yoshiya, Kamei, Yasuhiro, Watanabe, Masakatsu, Yamamoto, Kazuo, Hieda, Kotaro, Munakata, Nobuo, Ono, Tetsuya

Journal:

The Journal of Investigative Dermatology

Year:

2013

Language:

english

File:

PDF, 398 KB

english, 2013

21

In Vivo Spectrum of UVC-induced Mutation in Mouse Skin Epidermis May Reflect the Cytosine Deamination Propensity of Cyclobutane Pyrimidine Dimers

Ikehata, Hironobu, Mori, Toshio, Yamamoto, Masayuki

Journal:

Photochemistry and Photobiology

Year:

2015

Language:

english

File:

PDF, 398 KB

english, 2015

22

Wavelength‐ and Tissue‐dependent Variations in the Mutagenicity of Cyclobutane Pyrimidine Dimers in Mouse Skin

Ikehata, Hironobu, Mori, Toshio, Kamei, Yasuhiro, Douki, Thierry, Cadet, Jean, Yamamoto, Masayuki

Journal:

Photochemistry and Photobiology

Year:

2019

File:

PDF, 2.14 MB

2019

23

Analysis of mutation spectra in UVB-exposed mouse skin epidermis and dermis: Frequent occurrence of C→T transition at methylated CpG-associated dipyrimidine sites

Hironobu Ikehata, Toshinari Masuda, Hiroyuki Sakata, Tetsuya Ono

Journal:

Environmental and Molecular Mutagenesis

Year:

2003

Language:

english

File:

PDF, 233 KB

english, 2003

24

UVA1 Genotoxicity Is Mediated Not by Oxidative Damage but by Cyclobutane Pyrimidine Dimers in Normal Mouse Skin

Ikehata, Hironobu, Kawai, Kazuaki, Komura, Jun-ichiro, Sakatsume, Ko, Wang, Liangcheng, Imai, Masaru, Higashi, Shoichi, Nikaido, Osamu, Yamamoto, Kazuo, Hieda, Kotaro

Journal:

The Journal of Investigative Dermatology

Year:

2008

Language:

english

File:

PDF, 211 KB

english, 2008

25

Distribution of spontaneous CpG-associated G:C → A:T mutations in the lacZ gene of Muta™ mice: Effects of CpG methylation, the sequence context of CpG sites, and severity of mutations on the activity of the lacZ gene product

Hironobu Ikehata, Masaki Takatsu, Yusuke Saito, Tetsuya Ono

Journal:

Environmental and Molecular Mutagenesis

Year:

2000

Language:

english

File:

PDF, 274 KB

english, 2000

26

Mechanistic considerations on the wavelength-dependent variations of UVR genotoxicity and mutagenesis in skin: the discrimination of UVA-signature from UV-signature mutation

Ikehata, Hironobu

Journal:

Photochemical & Photobiological Sciences

Year:

2018

Language:

english

File:

PDF, 1023 KB

english, 2018

27

Mutation spectrum in UVB-exposed skin epidermis of Xpa-knockout mice: Frequent recovery of triplet mutations

Hironobu Ikehata, Fumitaka Yanase, Toshio Mori, Osamu Nikaido, Kiyoji Tanaka, Tetsuya Ono

Journal:

Environmental and Molecular Mutagenesis

Year:

2007

Language:

english

File:

PDF, 260 KB

english, 2007

28

XPC is involved in genome maintenance through multiple pathways in different tissues

Yoshihiko Uehara, Hironobu Ikehata, Maiko Furuya, Sayaka Kobayashi, Dongwei He, Yali Chen, Jun-ichiro Komura, Hiroshi Ohtani, Isao Shimokawa, Tetsuya Ono

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2009

Language:

english

File:

PDF, 709 KB

english, 2009

29

Mutation induction with UVB in mouse skin epidermis is suppressed in acute high-dose exposure

Hironobu Ikehata, Tetsuya Ono

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2002

Language:

english

File:

PDF, 104 KB

english, 2002

30

Skin can control solar UVR-induced mutations through the epidermis-specific response of mutation induction suppression

Ikehata, Hironobu, Munakata, Nobuo, Ono, Tetsuya

Journal:

Photochemical & Photobiological Sciences

Year:

2013

Language:

english

File:

PDF, 1.99 MB

english, 2013

31

Solar-UV-signature mutation prefers TCG to CCG: extrapolative consideration from UVA1-induced mutation spectra in mouse skin

Ikehata, Hironobu, Kumagai, Jun, Ono, Tetsuya, Morita, Akimichi

Journal:

Photochemical & Photobiological Sciences

Year:

2013

Language:

english

File:

PDF, 226 KB

english, 2013

32

A model for triplet mutation formation based on error-prone translesional DNA synthesis opposite UV photolesions

Hironobu Ikehata, Tetsuya Ono, Kiyoji Tanaka, Takeshi Todo

Journal:

Year:

2007

Language:

english

File:

PDF, 257 KB

english, 2007

33

Mutation spectrum in sunlight-exposed mouse skin epidermis: small but appreciable contribution of oxidative stress-mediated mutagenesis

Hironobu Ikehata, Shingo Nakamura, Takaaki Asamura, Tetsuya Ono

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2004

Language:

english

File:

PDF, 180 KB

english, 2004

34

Remarkable induction of UV-signature mutations at the 3′-cytosine of dipyrimidine sites except at 5′-TCG-3′ in the UVB-exposed skin epidermis of xeroderma pigmentosum variant model mice

Ikehata, Hironobu, Chang, Yumin, Yokoi, Masayuki, Yamamoto, Masayuki, Hanaoka, Fumio

Journal:

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

35

Fully functional global genome repair of (6-4) photoproducts and compromised transcription-coupled repair of cyclobutane pyrimidine dimers in condensed mitotic chromatin

Jun-ichiro Komura, Hironobu Ikehata, Toshio Mori, Tetsuya Ono

Journal:

Experimental Cell Research

Year:

2012

Language:

english

File:

PDF, 774 KB

english, 2012

36

Age-associated increase of spontaneous mutant frequency and molecular nature of mutation in newborn and old lacZ-transgenic mouse

Tetsuya Ono, Hironobu Ikehata, Shingo Nakamura, Yusuke Saito, Yoshio Hosoi, Yoshihiro Takai, Shogo Yamada, Junichi Onodera, Kazuo Yamamoto

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2000

Language:

english

File:

PDF, 213 KB

english, 2000

37

A phosphatidylinositol 3-kinase inhibitor wortmannin induces radioresistant DNA synthesis and sensitizes cells to bleomycin and ionizing radiation

Yoshio Hosoi, Hideo Miyachi, Yoshihisa Matsumoto, Hironobu Ikehata, Jun-ichiro Komura, Keiichiro Ishii, Heng-Jiang Zhao, Masayuki Yoshida, Yoshihiro Takai, Shougo Yamada, Norio Suzuki, Tetsuya Ono

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 98 KB

english, 1998

38

Absence of Mutagenic Effects of 2.45 GHz Radiofrequency Exposure in Spleen, Liver, Brain, and Testis of lacZ-Transgenic Mouse Exposed in Utero

Ono, Tetsuya, Saito, Yusuke, Komura, Jun-ichiro, Ikehata, Hironobu, Tarusawa, Yoshiaki, Nojima, Toshio, Goukon, Katsuo, Ohba, Yoshifumi, Wang, Jianqing, Fujiwara, Osamu, Sato, Risaburo

Journal:

The Tohoku Journal of Experimental Medicine

Year:

2004

Language:

english

File:

PDF, 478 KB

english, 2004

39

Tissue-specificity of age-dependent accumulation of mutations in digestive tract of mouse

Tetsuya Ono, Hironobu Ikehata

Journal:

Geriatrics & Gerontology International

Year:

2004

Language:

english

File:

PDF, 80 KB

english, 2004

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